Recent Publications

Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes Diabetes 2018 Jan; db170021

Deborah Kronenberg-Versteeg, Martin Eichmann, Mark A. Russell, Arnoud de Ru, Beate Hehn, Norkhairin Yusuf, Peter A. van Veelen, Sarah J. Richardson, Noel G. Morgan, Marius K. Lemberg and Mark Peakman

Diabetes 2018 Jan; db170021

Copy Of -Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes

Wedgewood KC, Richardson SJ, Morgan NG, Tsaneva-Atanasova K

Front Physiol Dec 27/7: 633

Islet cell hyperexpression of HLA class 1 antigens : a defining feature in type 1 diabetes

Sarah J. Richardson, Teresa Rodriguez-Calvo, Ivan C. Gerling, Clayton E. Mathews, John S. Kaddis, Mark A. Russell, Marie Zeissler, Pia Leete, Lars Krogvold, Knut Dahl-Jørgensen, Matthias von Herrath, 

Alberto Pugliese, Mark A. Atkinson, Noel G. Morgan

Diabetologia Nov 59(11): 2448-58, 2016

Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes.

Leete P, Willcox A, Krogvold, Dahl-Jørgensen, Foulis, Richardson SJ, Morgan NG.

Diabettes 65: 1362–1369,2016

The Subcellular distribution of cylin - D1 and cyclin - D3 within human islet cells varies according to the status of the pancreas donor.

Taniguchi K, M.A. Russell, Morgan NG, Richardson SJ.

 

Diabetologia 58: 2056–20631,2015

Islet Inflammation in Human Type 1 Diabetes Mellitus

Morgan NG, Leete P, Foulis AK, Richardson SJ. 

IUBMB Life;66:723-734, 2014 11

Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes.

Krogvold L, Edwin B, Buanes T, Frisk G, Skog O, Anagandula M, Korsgren O, Undien D, Eike MC, Rochardson SJ, Leete P, Morgan NG, Oikarinen S, Oikarinen M, Laiho JE, Hyöty H, Ludviqsson J, Hanssen KF, Dahl - Dahl-Jørgensen K.  

Diabetes; 64:1682-1687,2015

Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes.

 Arif S, Leete P, Richardson SJ, Nquyen V, Marks K, nor NM, Estorninho M, Kronenberg - Versteeq D, Bingley PJ, Todd JA, Guy C, Dunger DB, Powrie J, Wilcox A, Foulis AK, Rchardson SJ, de Rinaldis E, Morgan NG, Lorenc A, Peakman M.  

Diabetes;64:1682-1687, 2015

Enteroviruses as causative agents in type 1 diabetes: loose ends or lost cause?

Morgan NG,Richardson SJ.

Trends Endocrinol Metab;25:611-619,2014

Infection of human islets of langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway.

Anagandula M, Richardson SJ, Oberste MS, Sioofy-Khojine AB, Hyöty H, Morgan NG, Korsgren O, Frisk G. 

J Med Virol;86:1402-1411, 2014

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease.

Flanagan SE, Haapaniemi E, Russell M, Caswell R, Lango Allen H, De Franco E, McDonald TJ, Rajala H4, Ramelius A, Barton J, Heiskanen K, Heiskanen-Kosma T, Kajosaari M, Murphy NP, Milenkovic T, Seppänen M, Lernmark Å, Mustjoki S, Otonkoski T, Kere J, Morgan NG, Ellard S, Hattersley AT.

Nat Genet;46:812-814, 2014

GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans.

Stone VM, Dhayal S, Brocklehurst KJ, Lenaghan C, Sörhede Winzell M, Hammar M, Xu X, Smith DM, Morgan NG.

Diabetologia;57:1182-119, 2014

The impact of anti-inflammatory cytokines on the pancreatic β-cell.

Russell MA, Morgan NG.

Islets;6:e950547, 2014

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].

Richardson SJ1, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ; nPOD-V Consortium, Foulis AK, Frisk G, Flodstrom-Tullberg M, Hober D, Hyoty H, Morgan NG.

Diabetologia;57:647-649, 2014

Copy Of -Pancreatic pathology in type 1 diabetes mellitus

Richardson SJ, Leete P, Morgan NG, Foulis AK

Endochrine Pathology 25 80-92, 2014

Copy Of -Evaluation of the fidelity of immunolabelling obained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1 in human pancreas

Richardson SJ1, Leete P, Dhayal S, Russell MA, Oikarinen M, Laiho JE, Svedin E, Lind K, Rosenling T, Chapman N, Bone AJ; nPOD-V Consortium, Foulis AK, Frisk G, Flodstrom-Tullberg M, Hober D, Hyoty H, Morgan NG.

Diabetologia 57: 392-401, 2014

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